A research project being conducted in Melbourne is entering the trial phase of a non-invasive, cost-effective eye test to detect early signs of Alzheimer’s disease. The project has received $600,000 in funding from a major coalition of American philanthropists known as the Alzheimer’s Drug Discovery Foundation, which includes the likes of Bill Gates and MacKenzie Bezos.
Researchers from the Centre for Eye Research Australia (CERA) will fast track the development of the test and start clinical trials in August. The world-first eye scan trial will use coloured light to look through the retina for abnormal proteins that build up in the brain. The technology is similar to that used in NASA satellites.
The camera technology developed by Associate Professor Peter van Wijngaarden and Dr Xavier Hadoux, from CERA and the University of Melbourne, will measure the amyloid beta in the retina many years before symptoms of the disease appear.
Associate Professor van Wijngaarden said the approach had the potential to revolutionise the diagnosis of Alzheimer’s disease.
The current testing to diagnose Alzheimer’s disease is expensive and invasive, and the costs and limited availability of the tests render them out of reach for most healthcare systems. The innovative eye test could accelerate efforts to delay, prevent or even cure the disease, as it has the potential to enable scientists to take a more targeted approach to testing new drugs and treatments for those with a higher risk of diagnosis.
The test is being offered to middle-aged adult volunteers in Melbourne who have a history of Alzheimer’s disease. If you are interested in volunteering you can find more information on the Healthy Brain Project website or by emailing firstname.lastname@example.org
I suffered from brain aneurysm rupture in 2016. Whilst I looked well and have no obvious physical disabilities, I still suffer from executive dysfunction which includes emotional disturbances, short term/long term memory issues, finding words, spatial issues just to name a few. My parents are diagnosed with Alzheimer's and vascular dementia. I discovered dementia is common in my maternal side of the family. With my medical background and familial factors predispose me to have this condition in the future? I also would like to volunteer for the eye test to detect dementia earlier, please advice me how.
I am 67 & think I have a problem. Had single artery bypass 2007 & since that time have had changes with speech( stumbling on words or getting parts of words in reverse) can be long gaps when recalling memories. These issues come & go. Would like to know how to get the answer. Do I have dementia? I am in Brisbane
Hi, both my parents had Alzheimer’s and I am now 65 and concerned that I may have started down the same road. I am finding that most people - GP, family etc make the comment that they see nothing indicative of Alzheimer’s. But as a scientist and ultra sensitive to changes in my brain capacity, I know that I am changing and I am very keen t participate in this study. Would this be possible ? Given I live in Perth WA? I am sure there would be facilities here to look at amyloid protein in the eye. I know Prof Ralph Martins (professionally) and I feel sure he would be able to collaborate, Kind regards Susan Lewis
My mother died at 79 with Alzheimer’s disease for approx 10 years I’m 61 and am keen to be involved in your testing I live at Manly, suburbs of Sydney